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Automatic Cardiac Risk Management Classification using large-context Electronic Patients Health Records

arXiv cs.CL / 3/11/2026

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Key Points

  • The study presents an automated classification framework for cardiovascular risk management by analyzing unstructured electronic health records (EHRs) of geriatric patients.
  • Researchers benchmarked three modeling approaches: classical machine learning, specialized deep learning models optimized for large-context sequences, and general-purpose generative large language models (LLMs) in a zero-shot scenario.
  • A late fusion technique was applied to combine unstructured clinical text with structured medication and anthropometric data for improved performance.
  • The custom Transformer-based model with hierarchical attention mechanisms outperformed both traditional and generative LLM approaches, achieving the best F1-scores and Matthews Correlation Coefficients.
  • This approach offers a reliable, automated alternative to manual coding workflows for clinical risk stratification in cardiovascular healthcare management.

Computer Science > Computation and Language

arXiv:2603.09685 (cs)
[Submitted on 10 Mar 2026]

Title:Automatic Cardiac Risk Management Classification using large-context Electronic Patients Health Records

View a PDF of the paper titled Automatic Cardiac Risk Management Classification using large-context Electronic Patients Health Records, by Jacopo Vitale and 7 other authors
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Abstract:To overcome the limitations of manual administrative coding in geriatric Cardiovascular Risk Management, this study introduces an automated classification framework leveraging unstructured Electronic Health Records (EHRs). Using a dataset of 3,482 patients, we benchmarked three distinct modeling paradigms on longitudinal Dutch clinical narratives: classical machine learning baselines, specialized deep learning architectures optimized for large-context sequences, and general-purpose generative Large Language Models (LLMs) in a zero-shot setting. Additionally, we evaluated a late fusion strategy to integrate unstructured text with structured medication embeddings and anthropometric data. Our analysis reveals that the custom Transformer architecture outperforms both traditional methods and generative \acs{llm}s, achieving the highest F1-scores and Matthews Correlation Coefficients. These findings underscore the critical role of specialized hierarchical attention mechanisms in capturing long-range dependencies within medical texts, presenting a robust, automated alternative to manual workflows for clinical risk stratification.
Comments:
Subjects: Computation and Language (cs.CL); Artificial Intelligence (cs.AI); Information Retrieval (cs.IR)
MSC classes: 68T50
ACM classes: I.2.7
Cite as: arXiv:2603.09685 [cs.CL]
  (or arXiv:2603.09685v1 [cs.CL] for this version)
  https://doi.org/10.48550/arXiv.2603.09685
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arXiv-issued DOI via DataCite

Submission history

From: Bram van Es [view email]
[v1] Tue, 10 Mar 2026 13:55:42 UTC (269 KB)
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