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Composed Vision-Language Retrieval for Skin Cancer Case Search via Joint Alignment of Global and Local Representations

arXiv cs.CV / 3/11/2026

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Key Points

  • The paper presents a transformer-based framework for skin cancer case retrieval that jointly aligns global and local representations of vision-language queries.
  • It addresses composed queries combining lesion images and textual descriptors, matching them against a database of biopsy-confirmed multi-class disease cases.
  • The method uses hierarchical query representation with spatial attention masks for discriminative local region alignment and holistic global semantic supervision.
  • Experiments on the Derm7pt dataset show the approach outperforms existing state-of-the-art retrieval methods, enhancing clinical relevance and decision support.
  • This framework facilitates practical clinical deployment by enabling efficient access to relevant medical records, supporting diagnosis, education, and quality control.

Computer Science > Computer Vision and Pattern Recognition

arXiv:2603.09108 (cs)
[Submitted on 10 Mar 2026]

Title:Composed Vision-Language Retrieval for Skin Cancer Case Search via Joint Alignment of Global and Local Representations

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Abstract:Medical image retrieval aims to identify clinically relevant lesion cases to support diagnostic decision making, education, and quality control. In practice, retrieval queries often combine a reference lesion image with textual descriptors such as dermoscopic features. We study composed vision-language retrieval for skin cancer, where each query consists of an image to text pair and the database contains biopsy-confirmed, multi-class disease cases. We propose a transformer based framework that learns hierarchical composed query representations and performs joint global-local alignment between queries and candidate images. Local alignment aggregates discriminative regions via multiple spatial attention masks, while global alignment provides holistic semantic supervision. The final similarity is computed through a convex, domain-informed weighting that emphasizes clinically salient local evidence while preserving global consistency. Experiments on the public Derm7pt dataset demonstrate consistent improvements over state-of-the-art methods. The proposed framework enables efficient access to relevant medical records and supports practical clinical deployment.
Subjects: Computer Vision and Pattern Recognition (cs.CV); Artificial Intelligence (cs.AI)
Cite as: arXiv:2603.09108 [cs.CV]
  (or arXiv:2603.09108v1 [cs.CV] for this version)
  https://doi.org/10.48550/arXiv.2603.09108
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arXiv-issued DOI via DataCite

Submission history

From: Yuheng Wang [view email]
[v1] Tue, 10 Mar 2026 02:42:30 UTC (3,375 KB)
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