NeuroAI and Beyond: Bridging Between Advances in Neuroscience and ArtificialIntelligence

arXiv cs.AI / 4/22/2026

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Key Points

  • The paper argues that neuroscience and AI have progressed independently and identifies three key capability gaps in today’s AI: limited physical-world interaction, brittle learning, and high energy/data inefficiency.
  • It proposes neuroscience-inspired principles to address these gaps, including body–controller co-design, prediction via interaction, neuromodulated multi-scale learning, hierarchical distributed architectures, and sparse event-driven computation.
  • The authors lay out a research roadmap with near-, mid-, and long-term goals organized around those principles.
  • They emphasize that success will require training a new generation of researchers bridging neuroscience and engineering, supported by institutional measures such as cross-disciplinary curricula, hardware access, community standards, and ethics.
  • The work positions “NeuroAI” as a path to both improving AI systems and advancing scientific understanding of biological neural computation.

Abstract

Neuroscience and Artificial Intelligence (AI) have made impressive progress in recent years but remain only loosely interconnected. Based on a workshop convened by the National Science Foundation in August 2025, we identify three fundamental capability gaps in current AI: the inability to interact with the physical world, inadequate learning that produces brittle systems, and unsustainable energy and data inefficiency. We describe the neuroscience principles that address each: co-design of body and controller, prediction through interaction, multi-scale learning with neuromodulatory control, hierarchical distributed architectures, and sparse event-driven computation. We present a research roadmap organized around these principles at near, mid, and long-term horizons. We argue that realizing this program requires a new generation of researchers trained across the boundary between neuroscience and engineering, and describe the institutional conditions: interdisciplinary training, hardware access, community standards, and ethics, needed to support them. We conclude that NeuroAI, neuroscience-informed artificial intelligence, has the potential to overcome limitations of current AI while deepening our understanding of biological neural computation.