Multi-Stage Bi-Atrial Segmentation Framework from 3D Late Gadolinium-Enhanced MRI using V-Net Family Models

arXiv cs.AI / 4/30/2026

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Key Points

  • The paper proposes a multi-stage pipeline for multi-class bi-atrial segmentation from 3D late gadolinium-enhanced (LGE) cardiac MRI using V-Net family models.
  • It first preprocesses the input with multidimensional contrast limited adaptive histogram equalization (MCLAHE) to improve image quality before segmentation.
  • The approach performs coarse segmentation on MCLAHE-enhanced, down-sampled MRI using a V-Net variant, then refines the result with a second V-Net trained to produce fine segmentation from the coarse region.
  • Training uses an asymmetric loss function to optimize model weights for the segmentation task.
  • The work is published as an arXiv announcement (cross), indicating a research contribution rather than an deployed product or clinical release.

Abstract

We report our multi-stage framework designed for the problem of multi-class bi-atrial segmentation from 3D late gadolinium-enhanced (LGE) MRI of the human heart. The pipeline consists of a preprocessing step using multidimensional contrast limited adaptive histogram equalization (MCLAHE); coarse region segmentation from MCLAHE-enhanced and down-sampled MRI using a V-Net family model; and fine segmentation from the coarse region using another V-Net model. Asymmetric loss is adopted to optimize the model weights.